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IgAN unclear at first (Japan)

A 42-year-old man. Over the past three years, annual health checkups revealed proteinuria and hematuria, but no further evaluation was pursued. In year X, renal dysfunction was also detected on examination, and a renal biopsy was performed for further investigation.

Past Medical History: None

Medications: None

Family History: His mother has a history of hemodialysis

 

Vital parameters: 

BP: 143/92 mmHg 

HR: 65/min 

SpO2: 98 % 

 

Laboratory Findings:

Urinalysis;

RBCs: 20–29/HPF, WBCs: 1–4/HPF, 24-hour urine protein: 1400 mg/day

 

Blood Tests;

WBC: 7,000/μL, Hb: 14.5 g/dL, Platelets: 300,000/μL, TP: 7.0 g/dL, Alb: 4.3 g/dL, BUN: 18.5 mg/dL, Cr: 1.20 mg/dL, eGFR: 50.5 mL/min/1.73 m²,HbA1c: 5.5%, CRP: 0.02 mg/dL, IgG: 1300 mg/dL, IgA: 330 mg/dL, IgM: 125 mg/dL, C3: 80 mg/dL, C4: 52 mg/dL, ANA: <1:40, P-ANCA: Negative, C-ANCA: Negative, Anti-GBM antibody: Negative.

 

Note related to annotations: To avoid obscuring the lesions, the annotations are deliberately positioned close to, but not directly over, the lesion areas.