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IgAN less agressive progression (Japan)

A 25-year-old man underwent a renal biopsy for further evaluation after abnormalities in his urinalysis were identified during a routine health check-up.

Past Medical History: None

Medications: None

Family History: His father has a history of renal dysfunction.

 

Vital parameters: 

BP: 119/67 mmHg 

HR: 68/min 

SpO2: 99 % 

 

Physical Examination:

Physical examination revealed no abnormalities.

 

Laboratory Findings:

Urinalysis:

RBCs: 10–19/HPF, WBCs: 1–4/HPF, 24-hour urine protein: 1100 mg/day

 

Blood Tests:

WBC: 5,700/μL, Hb: 14.9 g/dL, Platelets: 253,000/μL, TP: 6.9 g/dL, Alb: 4.2 g/dL, BUN: 11.8 mg/dL, Cr: 1.00 mg/dL, eGFR: 29.6 mL/min/1.73 m², HbA1c: 5.8%, CRP: 0.01 mg/dL, IgG: 1273 mg/dL, IgA: 341 mg/dL, IgM: 100 mg/dL, C3: 91 mg/dL, C4: 51 mg/dL, ANA Titer: 1:40 c-ANCA : negative p-ANCA : negative.

 

Note related to annotations: To avoid obscuring the lesions, the annotations are deliberately positioned close to, but not directly over, the lesion areas.