Part A: Clinical information
Gender, Age
Male, 52 years old
Previous illnesses
None
Time period since the onset of the first symptoms
Very short: proteinuria detected during a medical check-up after which patient was referred to a nephrologist
Presentation
Rapid decline of eGFR in 2 months accompanied by proteinuria. No hematuria. No history of kidney disease in the family. Otherwise healthy man.
Laboratory parameters
Proteinuria: 1.3 grams.
M protein: negative
eGFR: 24
ANCA negative.
Why was the decision made for a biopsy?
Relatively rapidly progressive renal function deterioration of unknown cause.
How long after the first symptoms was the biopsy conducted?
Approximately 2 months.
Suspected diagnosis of the indication for biopsy?
The clinical question was: explanation for renal insufficiency? TIN? Other?
Note related to annotations: To avoid obscuring the lesions, the annotations are deliberately positioned close to, but not directly over, the lesion areas.