Part A: Clinical information
Gender, Age
Boy, 12 years old
Previous illnesses
Nephrotic syndrome that is steroid resistant
Time period since the onset of the first symptoms
Approximately 2 years
Presentation
Initial presentation: foamy urine; nephrotic range proteinuria with mild hematuria. No preceding event, no infectious disease. Renal function overall preserved. After initial treatment nephrotic range proteinuria recurred.
Laboratory parameters
Erythrocyturia and proteinuria. ANA/ANCA/anti-GBM negative.
Anti-PLA2R negative. No leucocyturia. Few casts.
Why was the decision made for a biopsy?
The persistent proteinuria in nephrotic range was the main reason for biopsy.
How long after the first symptoms was the biopsy conducted?
2 years
Suspected diagnosis of the indication for biopsy?
Minimal Change Disease / FSGS?
Note related to annotations: To avoid obscuring the lesions, the annotations are deliberately positioned close to, but not directly over, the lesion areas.