Part A: Clinical information
Gender, Age
Female, 50 years old
Previous illnesses
Sjögren’s disease
Time period since the onset of the first symptoms
Has had Sjögren’s disease for years, but now appears to be accompanied by a slowly progressive kidney function deterioration.
Presentation
No other symptoms related to kidney involvement – renal function deterioration detected during medical check-up.
Laboratory parameters
Proteinuria (dipstick): +
Renal function: chronically deteriorating.
Why was the decision made for a biopsy?
The combination of clinical and serological parameters are indicative for taking a kidney biopsy to confirm whether there is kidney involvement associated with Sjögren’s disease or another cause.
How long after the first symptoms was the biopsy conducted?
The biopsy was conducted at an unknown time point after kidney involvement.
Suspected diagnosis of the indication for biopsy?
TIN associated with Sjögren’s disease?
Note related to annotations: To avoid obscuring the lesions, the annotations are deliberately positioned close to, but not directly over, the lesion areas.